What is Unisom SleepGels?

With the hustle and bustle of daily life, people can often forget exactly how important it is to get a good night’s rest. Remember that objects (and people) in motion tend to stay in motion so even if you may be physically exhausted from a full day of work, your body may not shut off as quickly as you would like. That’s where Unisom SleepGels come in. They claim to use a simple formulation to ensure that you fall asleep in no time and that you stay asleep for longer to ensure you are fully recharged for the next busy day.


Unisom SleepGels, unlike other sleep support supplements which have a complicated formulation with numerous ingredients, has only one ingredient which is Diphenhydramine HCl at 50mg. This is a type of antihistamine that can make you feel sleepy.

If that sounds familiar to you, antihistamines are anti-allergy medications which are well known to cause drowsiness as its main side effect. So Unisom SleepGels (though not mentioned) may work as an anti-allergy medication as well, though it is entirely possible that this product is marketed for its side effect and not for its anti-allergy purposes.


Unisom recommends that one SleepGel capsule should be taken before bedtime or as needed.


Unisom SleepGels are not sold directly from their website but is offered at a variety of retailers such as Walgreens, CVS, Amazon, Target or Walmart which sells a box of 60 capsules for $10.98.

Possible Side Effects

Caution is advised to anyone under the age of 12, pregnant women, and breastfeeding mothers. Antihistamines are not advised during pregnancy due to proven facts that it can be transmitted to the fetus. Antihistamines can also slow down or stop lactation. Unisom also advises that advice from a physician is sought before taking this supplement if you suffer specifically from any breathing problems, glaucoma, or have difficulty in urinating.

Other side effects mentioned by Unisom for this supplement include daytime drowsiness, dizziness, dry mouth, and problems relating to memory. It is advised that if any of these reactions are experienced to consult with a physician immediately.

Unisom also strongly mentions not to use this supplement with anything that has diphenhydramine.

Manufacturer’s Commitment

Though Unisom SleepGels have been deemed as the number one pharmacist’s choice for an over the counter sleep supplement, they do not have any guarantee in place anywhere on their website nor do they have customer reviews or testimonials to support the effects of their product.

There is also no evidence that supports Unisom SleepGels claims at effectivity nor are there any mentioned trials or studies that have been conducted.

The Bottom Line

Unisom SleepGels may provide a simple solution to sleep problems through their one ingredient supplement, but it is always important to remember that this sleep aid is first and foremost an anti-histamine or an anti-allergy medication and the primary purpose to which it is being marketed is actually only a secondary effect to its intended purpose.

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